Kaunas Hospital of the Lithuanian University of Health Sciences is one of the largest clinical research bases in Lithuania. Ongoing clinical researches:
| Medical field | The main executive department of Kaunas Hospital of LSMU | Type | Protocol No | Name | Principal Investigator | Start / End |
| Surgery | Surgery Department (Josvainių str. 2, Kaunas) | Medicinal preparations | BUX-4/UCA | A randomized, double-coded, active-controlled, phase III clinical study of two non-therapeutic agents 8 weeks. To determine the efficacy and safety of adjunctive treatment with budesonide 9 mg capsules compared to budesonide 6 mg capsules compared to budesonide MMX9 mg tablets in patients with ulcerative colitis treated with the standard drug mesalazine. | D. Venskutonis | 05/2019/ 05/2021 |
| Surgery | Surgery Department (Josvainių str. 2, Kaunas) | Medicinal preparations | APD334-301 | Phase III, double-coded, placebo-controlled, 52-week study to evaluate the efficacy and safety of erasimod in subjects with moderate to severe active ulcerative colitis | D. Venskutonis | 12/2019 / 06/2022 |
| Surgery | Surgery Department (Josvainių str. 2, Kaunas) | Medicinal preparations | APD334-302 | Phase III, double-coded, placebo-controlled, 12-week study to evaluate the efficacy and safety of erasimod in patients with moderate to severe active ulcerative colitis | D. Venskutonis | 04/2020 / 10/2022 |
| Urology | Urology Department (Josvainiu str. 2, Kaunas) | Medicinal preparations | URO-901-3005 | A phase 3, double-coded, randomized, placebo-controlled, multicentre study to evaluate the efficacy, safety, and tolerability of vibegron in men with symptoms of elevated bladder activity (CHP) treated for benign prostatic hyperplasia (BPH). | G. Rinkūnas | 01/2021 / 2022 |
| The main: Internal Diseases
Other: Clinical Pharmacology, Resuscitation, Urology, Surgery |
Department of Internal Medicine Diagnostics
Adult Emergency and Resuscitation Department No 2 Urology Department (Josvainiu str. 2, Kaunas) |
Medicinal preparations | CS2514-2017-0004 | A randomized, active-coded study to evaluate the efficacy and safety of intravenous Sulbactam-ETX2514 in patients with Acinetobacter baumannii-calcoaceticus infections | G. Gumbrevičius | 05/2019 / 07/2021 |
| The main: Internal Diseases
Other: Clinical Pharmacology, Cardiology, Nephrology |
Department of Hemodialysis
(Baltijos str. 120, Kaunas) |
Medicinal preparations | BAY 1213790 / 20115 | A randomized, double-blind, parallel-group, multicenter study to evaluate the tolerability and safety of once-monthly subcutaneous administration of low and high doses of osocimab in patients receiving regular hemodialysis for chronic renal failure. | G. Gumbrevičius | 10/2020 / 06/2023 |
| Pulmonology | Consulting Polyclinic (Josvainių str. 2, Kaunas)
Admission Emergency and Injury Department (Gedimino str. 36, Kaunas) |
Medicinal preparations | EFC15805 NOTUS | A randomized, double-blind, placebo-controlled, parallel-group, 52-week confirmatory study to evaluate the efficacy, safety, and tolerability of dupilimab in patients with moderate to severe COPD type 2 inflammation. | A. Bagdonas | 06/2020 / 08/2022 |
| Cardiology | Department of Internal Medicine (Laisvės av. 17, Kaunas) | Medicinal preparations | FINEARTIS-HF 20103 | Study of the efficacy and safety of finerenone compared to placebo in patients with heart failure | A. Bagdonas | 08/2020 / 08/2024 |
| Orthopedics Traumatology | Department of Orthopedic Traumatology No 1 (Laisvės av. 17, Kaunas) | Medicinal preparations | ANT-005 8412959 | A multicenter, randomized, open-label, coded, endpoint, active-controlled, multidose study to compare the efficacy and safety of intravenous MAA868 and subcutaneous enoxaparin in adult patients undergoing elective unilateral total knee replacement surgery. | J. Belickas | 06/2020 / 03/2021 |
| Rheumatology | Therapy Clinic Consulting Polyclinic (Hipodromo str. 13, Kaunas) | Biological therapy | CREDO 4 CL04041024 | Biological treatment of persons with rheumatoid arthritis | J. Dambrauskienė | 08/2017 / 03/2021 |
| Rheumatology | Therapy Clinic Consulting Polyclinic (Hipodromo str. 13, Kaunas) | Biological therapy | Glaxo Smith Kline 201790 | Biological treatment of persons with rheumatoid arthritis | J. Dambrauskienė | 11/2019 / 2024 |
| Rheumatology | Therapy Clinic Consulting Polyclinic (Hipodromo str. 13, Kaunas) | Biological therapy | LILY 14V-MC-JAJA | Biological treatment of persons with rheumatoid arthritis | J. Dambrauskienė | 07/2020 / 2027 |
Information:
Department of Studies, Science and Projects
E-mail: tyrimai@kaunoligonine.lt